Endocrine Abstracts

Background: Pseudo precocious puberty in young children usually arises from adrenal or less commonly testicular causes. Though rare, the possibility of an exogenous source should also be considered.Case Report: A 2 year 2 month old male child presented with apparent overgrowth since about 1 year of age. His height was 108 cms [+6.29 SDs], weight 21 kgs [+4.54 SDs] and head circumference 52.2 cms [2.76 SDs]. He looked very mature for his age but had no dy...

Background: Type A insulin resistance syndrome (TAIRS) is rare (prevalence 1/100 000) and is caused by pathological mutations in the insulin receptor (INSR) gene. The clinical features tend to affect females more severely. Patients can present with severe hyperinsulinemia, hyperandrogenism and acanthosis nigricans. We report a case of a girl with symptoms initially suggestive of polycystic ovarian syndrome (PCOS) but also with asymptomatic diabetes mellitus.<p class="abste...